Improving the Therapeutic Ratio in Head and Neck Cancer Volume 6 in Cancer Sensitizing Agents for Chemotherapy

Improving the Therapeutic Ratio in Head and Neck Cancer Volume 6 in Cancer Sensitizing Agents for Chemotherapy 2020 original pdf

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AUTHORS: Randall J. Kimple
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Improving the Therapeutic Ratio in Head and Neck Cancer Volume 6 in Cancer Sensitizing Agents for Chemotherapy 2020 original pdf

Improving the Therapeutic Ratio in Head and Neck Cancer provides a complete review of current approaches to modulating therapeutic sensitivity in head and neck cancer. It presents a broad background of current approaches and by highlighting the potential for clinical translational, introduces a roadmap for how to move promising preclinical findings into the clinic.

The book discusses topics such as immunotherapy and molecularly targeted therapies in head and neck cancer, PI3k/mTOR pathway, autophagy inhibition to sensitize HNC to radiation and chemotherapy, TAM and Eph/Ephrin family proteins and metabolic reprogramming to modulate therapeutic sensitivity. Additionally, it details approaches to improve the response to immunotherapy, and Chk1/2 inhibition in radiation and cetuximab resistance.

This book is a valuable source to head and neck cancer researchers and advanced students, and to those studying specific approaches in other model systems and disease sites.

AUTHORS: Randall J. Kimple

YEAR: 2020

PUBLICATION: Academic Press

LANGUAGE: English

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